Proving Negative Selection in the Thymus

Proving negative selection in the thymus.

Negative Selection in the Thymus Includes Semimature T Cells

The thymic medulla plays a key role in negative selection (self-tolerance induction) and contains differentiated T cells en route to the extrathymic environment. However, being relatively mature, medullary T cells are thought to be beyond the stage of tolerance induction. This paradox is resolved by the finding that medullary T cells (CD4+8- thymocytes) comprise two distinct subsets. Medullary ...

Negative Selection Algorithms: from the Thymus to V-detector

Ji, Zhou. Ph.D. The University of Memphis. August, 2006. Negative selection algorithms: from the thymus to V-detector. Major Professor: Dipankar Dasgupta, Ph.D. Artificial Immune Systems (AIS) is a research area of developing computational methods inspired by biological immune systems. The approach of negative selection algorithms (NSA) is one of the major models of AIS. This dissertation does ...

the test for adverse selection in life insurance market: the case of mellat insurance company

انتخاب نامساعد یکی از مشکلات اساسی در صنعت بیمه است. که ابتدا در سال 1960، توسط روتشیلد واستیگلیتز مورد بحث ومطالعه قرار گرفت ازآن موقع تاکنون بسیاری از پژوهشگران مدل های مختلفی را برای تجزیه و تحلیل تقاضا برای صنعت بیمه عمر که تماما ناشی از عدم قطعیت در این صنعت میباشد انجام داده اند .وهدف از آن پیدا کردن شرایطی است که تحت آن شرایط انتخاب یا کنار گذاشتن یک بیمه گزار به نفع و یا زیان شرکت بیمه ...

Positive and Negative Selection in the Thymus and the Thymic Paradox